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Ectropion

Writer's picture: Munib ur RehmanMunib ur Rehman

Updated: Feb 2, 2024

 

Inspection

On inspection, the patient has an eversion of the Right lower eye-lid margin.

 

Check for!

 

Facial Signs:

Signs of Facial nerve palsy – retraction of the upper eyelid and brow ptosis (at times mimicking narrowing of the palpebral aperture

Scar mark/s – appearance, color.

Mass causing eversion of the eyelid.

Midface hypoplasia

           

Eyelid Signs

Punctum - Eversion

Worsening of eversion on the opening of the mouth (cicatricial)

Horizontal and vertical palpebral fissure height

lagophthalmos,

amount of lid retraction

Lashes – loss of lashes, trichiasis

Loss of acute angle of the lateral canthus

Assess whether the ectropion is affecting the whole of the eyelid or any specific segment.

           

Conjunctiva –

Inflammation,

thickening and Keratinization of the conjunctiva,

shortening of fornices      

           

Cornea –

Exposure keratopathy

corneal vascularization

 

Look for other conditions caused by ocular/periocular trauma.

 

Palpation

Assess lid Laxity:

Horizontal Lid laxity – snap back test – the central part of the eyelid is pulled 8mm or more from the globe – it is positive if there is failure of the eyelid to snap back to its normal position on release without the first blink of the patient.

           

Lateral canthal tendon laxity – results in a change of the usual sharp appearance of lateral canthus to a more rounded one. Moreover, the lateral canthus can be pulled medially more than 2mm.

 

Medial Canthal Tendon laxity – exhibited by pulling the lower eyelid laterally and observing the position of the inferior punctum. Under normal conditions, the punctum is not displaced 1-2 mm. However, a movement of 5 mm indicates significant laxity of the medial canthal tendon.

 

 

Palpate the Scar for:

Extent of scar

Thickness of scar

Texture of scar

Scar maturity.

           

 

Facial architecture: Palpate the lower orbital rim to rule out hemi-proptosis.

 

Tests for ocular surface condition

Fluorescein stain

Tear film breakup time.

Schirmer test

 

Tests for lacrimal system patency

Dye disappearance test.

Jones Tests

 

Questions:

What are the causes of ectropion?

Involutional ectropion - increased horizontal laxity of the lower eyelid and disinsertion of the lower eyelid retractors.

Cicatricial ectropion - of the anterior lamella of the eyelid, comprised of the skin and orbicularis muscle.

Paralytic ectropion - decreased orbicularis muscle tone supporting the lower eyelid.

Mechanical ectropion can occur when a mass, such as a tumor, displaces the lower eyelid margin.

 

What are the risk factors for the development of ectropion?

The risk factors for the development of ectropion are as follows.

More common

Age (gravity, loss of elasticity)

Eyelid rubbing

Trauma

Less common

Repeated eyelid pulling (ex. contact-lens use)

Floppy eyelid syndrome

Long-term use of eye drops

Skin conditions which involve the eyelid

Prior Eyelid Surgery

 

What are the general principles of surgical treatment of ectropion?

Cause

Treatment

Lower eyelid laxity

Horizontal tightening by lateral tarsal strip or a similar procedure

Disinsertion of retractors of lower eyelid

Jones procedure to reattach the retractors to the inferior border of tarsal plate

Punctal Ectropion

Medial spindle procedure to reappose the everted punctum

Cicatricial ectropion

Lengthening of the anterior lamella by a skin graft

Paralytic Ectropion

Horizontal tightening and correction of punctal ectropion.

In extensive cases, a facelift may also be required.

 

What are the usual complications of Ectropion surgery?

Although ectropion surgery is relatively safe and effective, recurrences do occur and are often temporally associated. There is the possibility of local post-operative bleeding or infection. There is a remote possibility of injury to the cornea. 

 

How do we treat involutional ectropion?

The management depends on whether the ectropion is generalized or present only medially.

 

Generalized Ectropion: Usually, repair of horizontal lid laxity is enough to correct the condition best achieved by Lateral Tarsal Strip Procedure, especially when the lateral canthus has become rounded and allows for tear egress laterally. However, if there is an area of misdirected lashers or keratinized conjunctiva, a pentagon transconjunctival excision may be carried out; however, if there is medial canthal laxity, the tendon needs to be stabilized before horizontal shortening to avoid dragging of the punctum laterally, rendering it non-function.

 

Medial Ectropion: a diamond medial conjunctival diamond excision (medial spindle procedure), may be used to treat mild cases. This procedure can be combined with a tarsal strip, lateral canthal sling, or pentagon excision if significant horizontal laxity coexists.

 

Punctal ectropion: if there is pure punctal ectropion without much eyelid involvement, Ziegler cautery may be considered.

 

What are the treatment options for ectropion associated with Facial nerve palsy?

 

Temporary Measures:

 

As about 90% of cases of Bells’ Palsy are reversible, temporary measures may be initiated to protect the cornea and prevent corneal exposure.

Lubrication with high-viscosity substitutes

Ointment and Taping of eyelids during sleep

Botulinum toxin to levator palpebrae superioris to induce ptosis.

Temporary tarsorrhaphy

 

If Bells’ palsy doesn’t improve by 6-12 months, or there is irreversible damage to the facial nerve, permanent treatments should be considered.

 

 

Permanent measures:

 

Medial Canthoplasty

Lateral canthal sling or Lateral tarsal strip

Levator disinsertion to lower the upper eyelid.

Gold or platinum weight implants for lagophthalmos

lateral tarsorrhaphy

 

What is the Treatment of cicatricial ectropion?

As the primary cause of cicatricial ectropion is vertical shortening of the anterior eyelid lamella, the correction is focused on lengthening it.

Mild and localized cases are managed by excision of scar tissue combined with lengthening procedures such as Z-plasty. In contrast, severe generalized cases require transposition flaps or free skin grafts.

The skin may be harvested from upper eyelids, pre- or post-auricular areas, and supraclavicular areas.

 

How do you grade Ciccatricial Ectropion?

Grading of cicatricial ectropion

Grade I- Punctal eversion or a part of posterior lid margin not apposed to the globe.

Grade II- The whole length of the posterior lid margin is not apposed to the globe

Grade III- Palpebral conjunctiva visible.

Grade IV- Fornix is visible

 

What are the common causes of Cicatricial Ectropion?

Trauma

Burns

Cicatrizing skin tumors

Medications like dorzolamide, brimonidine

Allergies

Skin conditions – ichthyosis

 

In which eyelid is the involutional ectropion more common and why?

Involutional ectropion is more common because of gravity and smaller and relatively weak tarsal plate.

 

What is the optimal time for intervention in cases of cicatricial ectropion?

The process of scar maturation, reaching 70-80% tensile strength, typically spans 6 to 12 months. During this time, adjunct treatments like scar massage, silicone gel, steroids, and antimetabolites are essential to prevent hypertrophic scar formation. Early use of these agents post-trauma can lead to more aesthetically pleasing outcomes in the long run, as immature scars are prone to hypertrophy and may result in poor results after scar revision. 

 

What are non-surgical measures taken for management of Cicatricial Ectropion?

 

Scar massage

The massage should be initiated as early as possible and continued for 6-8 weeks after surgery 2, 3 times a day. This massage caused physical disruption of fibroblast fibers, rendering the wound more pliable and thus resulting in a softer scar.

 

Pressure therapy

It is considered the standard of care for burn scars. The compression over scar area aggravates the hypoxic state of the scar tissue, thereby increasing degeneration of fibroblasts and collagen.

 

Silicone gel

Silicone gel decreases capillary activity, vascularity and metabolism of the scar tissue by providing a hydrating environment of the epidermal layer.

 

Intra-lesional steroids

Intra-lesional injection of long-acting steroid inhibits keratinocyte proliferation, inflammatory compounds and has an anti-angiogenic effect. The dose and regimens vary between 1 to 40 mg/ml at 2–6 weeks’ intervals.

 

Non-ablative laser resurfacing

Non-ablative fractional laser resurfacing involves the use of a specific type of laser emitting at 1540 nm wavelength. This laser creates columns of thermal damage at specific depths, triggering a therapeutic wound healing response. The response includes the activation of heat shock proteins, myofibroblasts, and increased production of collagen III, ultimately contributing to texture remodeling..  

 

Autologous Fat graft for Cicatricial Ectropion

The technique has been widely used for first and second degree burn scars. Adipose tissue, housing stored fat and a reserve of mesenchymal stem cells, possesses the unique ability for indefinite multiplication of these cells. This property allows them to replace atrophied cells, offering the potential for the restoration of both full mechanical and biological properties.

 

What are the surgical Measures taken to correct cicatrical Ectropion?

The ectropion can be corrected with a Z-plasty. The central limb of the Z is madealong the line of the scar and the two peripheral limbs at about 60 degrees to this central limb. The flaps are raised and the underlying scar excised. Any residual eversion of the punctum may be treated with retropunctal cautery or tarsoconjunctival excision.

Skin graft 

 

What are the phases of wound healing?

 

Inflammatory phase: Whenever there is trauma, the inflammatory phase begins, which lasts for 4-6 days. The inflammatory phase is characterized by the presence of local edema, erythema, and pain.

Proliferative phase: The proliferative phase lasts for 4-24 days. The smaller blood vessels begin to increase, and granulation tissue fills the wound. Fibroblasts lay collagen in the wound bed, causing the granulation tissue to strengthen and wound edges begin to contract.

Maturation phase: The maturation phase lasts for 21 days to 2 years. Filled in the wound is strengthened, and scar tissue is formed. The length of the maturation phase varies.

 

 

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